Permuting the PGF-CTERM signature motif blocks both archaeosortase-dependent C-terminal cleavage and prenyl lipid attachment for the Haloferax volcanii S-layer glycoprotein
Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation
H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis
Monitoring cellular phosphorylation signaling pathways into chromatin and down to the gene level
Nitric oxide regulates gene expression in cancers by controlling histone posttranslational modifications
Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin
Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications
The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79
Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations
Comprehensive Catalog of Currently Documented Histone Modifications
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane
Properly reading the histone code by MS based proteomics
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity
Characterization of histone post-translational modifications during virus infection using mass spectrometry-based proteomics
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression
Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation
Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications
Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants
LLY-507, a Cell-Active, Potent and Selective Inhibitor of Protein Lysine Methyltransferase SMYD2
EpiProfile quantifies histone modifications by extracting retention time and intensity in high-resolution mass spectra
Bottom-Up and Middle-Down Proteomics Have Comparable Accuracies in Defining Histone Post-Translational Modification Relative Abundance and Stoichiometry
Characterization of BRD4 during mammalian post-meiotic sperm development
Quantitative Proteomic Analysis of Histone Modifications
A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation
Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis
SWATH Analysis for Characterization and Quantification of Histone Post-translational Modifications
The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression
Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis
Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia
Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, Zheng D, Jin J, Wang GG. Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. Blood. 2015, 125(2):346-57.