Publications in 2011

NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming

Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O. NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming. Mol Cell. 2011, 44, (4):609-20.

Isoform specific phosphorylation of human linker histone H1.4 in mitosis by Aurora B kinase

Hergeth, S.P.; Dundr, M.; Tropberger, P.; Zee, B.M.; Garcia, B.A.; Daujat, S.; Schneider, R. Isoform specific phosphorylation of human linker histone H1.4 in mitosis by Aurora B kinase. Journal of Cell Science, 2011, 124(Pt 10):1623-8.

Breaking the histone code with quantitative mass spectrometry

Britton, L.P.; Gonzales-Cope, M.; Zee, B.M.; Garcia, B.A. Breaking the histone code with quantitative mass spectrometry. Expert Rev. in Proteomics, 2011, 8(5):631-43.

Garcia B.A. Proteomic interrogation of human chromatin

Plazas-Mayorca, M.D.; Zee, B.M.; Young, N.L.; Baliban, R.C; Leroy, G.; Floudas, C.A.; Hake, S.B.; Garcia B.A. Proteomic interrogation of human chromatin. PLoS ONE, 2011, 6(9): e24747.

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

Korpal M., Ell, B,J,, Buffa, F.M., Ibrahim, T., Blanco, M.A., Celià-Terrassa, T., Mercatali, L., Khan, Z., Goodarzi, H., Hua, Y., Wei, Y., Hu, G., Garcia, B.A., Ragoussis, J., Amadori, D., Harris, A.L., Kang, Y. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Medicine, 2011, 17(9):1101-8.

Methylation of H2AR29 is a novel repressive PRMT6 target

Waldmann, T.; Izzo, A; Kamieniarz, K.; Richter, F.; Vogler, C.; Sarg, B.; Lindner H.; Young, N.L.; Mittler, G.; Garcia, B.A.; Schneider, R. Methylation of H2AR29 is a novel repressive PRMT6 target. Epigenetics and Chromatin, 2011, 4:11.

The RING finger protein MSL2 in the MOF complex Is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation

Wu, L.; Zee, B.M.; Wang, Y.; Garcia, B.A.; Dou Y. The RING finger protein MSL2 in the MOF complex Is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Molecular Cell, 2011, 43(1):132-44.

Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity

Yan, K.; Cao, Q.; Reilly, C.M.; Young, N.L.; Garcia, B.A.; Mishra, N. Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. Journal of Biological Chemistry, 2011, 286(33):28833-43.

UNC0638: Potent, Selective, and Cell-penetrant Chemical Probe of Protein Lysine Methyltransferases G9a and GLP

Vedadi, M; Barsyte-Lovejoy, D.; Liu, F.; Rival-Gervier, S.; Allali-Hassani, A.; Labrie, V.; Wigle, T.J.; DiMaggio, P.A.; Wasney, G.A.; Siarheyeva, A.; Dong, A.; Tempel, W.; Wang, S.; Chen, X.; Chau, I.; Mangano, T.J.; Huang, X.; Simpson, C.D.; Pattenden, S.G.; Norris, J.L.; Kireev, D.B.; Tripathy, A.; Edwards, A.; Roth, B.L.; Janzen, W.P.; Garcia, B.A.; Petronis, A.; Ellis, J.; Brown, P.J.; Frye, S.V.; Arrowsmith, C.H.; Jin, J. UNC0638: Potent, Selective, and Cell-penetrant Chemical Probe of Protein Lysine Methyltransferases G9a and GLP. Nat. Chem. Biol., 2011, 7(8):566-74.

Liquid Chromatography-Mass Spectrometry of Intact Proteins, a book chapter in “Protein and peptide analysis by LC-MS: Experimental strategies.”

Young, N.L.; Garcia, B.A. Liquid Chromatography-Mass Spectrometry of Intact Proteins, a book chapter in “Protein and peptide analysis by LC-MS: Experimental strategies.” Royal Society of Chemistry, 2011, 38-55.

Quantitative proteomic approaches to studying histone modifications

Zee, B.M.; Young, N.L.; Garcia, B.A. Quantitative proteomic approaches to studying histone modifications. Current Chemical Genomics, 2011, 5(Suppl 1):106-14.

Revealing histone variant induced chromatin changes via quantitative proteomics

Arnaudo, A.M.; Molden, R.C. Garcia, B.A., Revealing histone variant induced chromatin changes via quantitative proteomics. Crit Rev Biochem Mol Bio., 2011, 46(4):284-94.

Global turnover of histone post-translational modifications and variants in human cells

Zee, B.M.; Levin, R.S.; DiMaggio, P.A.; Garcia, B.A. Global turnover of histone post-translational modifications and variants in human cells. Epigenetics and Chromatin, 2010, 3:22. (#1 downloaded publication for Epigenetics and Chromatin Journal of 2011)

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

Levy, D.; Kuo, A.J.; Chang, Y.; Schaefer, U.; Kitson, C.; Cheung, P.; Espejo, A.; Zee, B.M.; Tangsombatvisit, S.; Tennen, R.I.; Kuo, A.Y.; Tanjing, S.; Liu, C.L.; Cheung, R.; Utz, P.J.; Chua, K.; Shi, X.; Prinjha, R.; Garcia, B.A. Bedford, M.T.; Tarakhovsky, A.; Cheng, X.; Gozani, O. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nature Immunology, 2011, 12, (1), 29-36.