Publications in 2010

Ueberheide, B.M

Garcia, B.A.; Cooper, H.J.; Dorrestein, P.C.; Tang, K.; Ueberheide, B.M. J Biomed Biotechnol. 2010, 2010:453045.

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

Kapoor, A.; Goldberg, M.S.; CumberlandL.K.; Ratnakumar, K.; Segura, M.F.; Emanuel, P.O.; Menendez, C.; Vardabasso, S.; LeRoy, G.; Vidal, C.I.; Polsky, D.; Osman, I.; Garcia, B.A.; Hernando, E.; Bernstein, E. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature, 2010, 468, (7327), 1105-1109.

Histone H3 lysine 9 methyltransferases activity is inhibited by the euchromatic mark H3K4me3: Regulation of lysine methyltransferases by physical interaction with their substrates

Binda, O.; Leroy, G.; Bua, D.J.; Garcia, B.A.; Gozani, O.; Richard, S. Histone H3 lysine 9 methyltransferases activity is inhibited by the euchromatic mark H3K4me3: Regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics, 2010, 5, (8), 767-775.

The significance, development and progress of high-throughput combinatorial histone code analysis

Young, N.L.; DiMaggio, P.A.; Garcia, B.A. The significance, development and progress of high-throughput combinatorial histone code analysis. Cellular and Molecular Life Sciences, 2010, 67, (23), 3983-4000.

The mental retardation gene PHF8 mediates histone H4K20/H3K9 demethylation and regulates zebrafish brain apoptosis and craniofacial development

Qi, H.H.; Sarkissian, M.; Hu, G-Q.; Wang, Z.; Bhattacharjee, A.; Gordon, D.B.; Gonzales, M.; Lan, F.; Ongusaha, P.P.; Huarte, M.; Yaghi, N.K.; Lim, H.; Garcia, B.A.; Brizuela, L.; Zhao, K.; Roberts, T.M.; Shi, Y. The mental retardation gene PHF8 mediates histone H4K20/H3K9 demethylation and regulates zebrafish brain apoptosis and craniofacial development. Nature, 2010, 466, (7305), 503-507.

Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown

Plazas-Mayorca, M.D.; Bloom, J.S.; Zeissler, U.; Leroy, G.; Young, N.L.; DiMaggio, P.A.; Krugylak, L.; Schneider, R.; Garcia, B.A. Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown. Molecular BioSystems, 2010, 6, (9), 1719-1729.

Branched tricarboxylic acid metabolism in Plasmodium falciparum

Olszewski, K.L.; Mather, M.W.; Morrisey, J.M.; Garcia, B.A.; Vaidya, A.B.; Rabinowitz, J.D.; Llinas, M. Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature, 2010, 466, (7307), 774-778.

Mass spectrometry based proteomics for interrogating the histone code

DiMaggio, P.A.; Garcia, B.A. Mass spectrometry based proteomics for interrogating the histone code. Current Proteomics, 2010, 7, (3), 177-187.

Modern approaches for investigating epigenetic signaling pathways

Evertts, A.G.; Zee, B.M.; Garcia, B.A. Modern approaches for investigating epigenetic signaling pathways. Journal of Applied Physiology, 2010, 109, 927-933.

H1 variant specific lysine methylation by G9a/KMT1C and Glp1/KMT1D

Weiss, T.; Daujat, S.; Zee, B.M.; Garcia, B.A.; Schneider, R., H1 variant specific lysine methylation by G9a/KMT1C and Glp1/KMT1D. Epigenetics and Chromatin, 2010, 3, (1), 7.

Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a

Young, N.L.; Plazas-Mayorca, M.D.; Flaniken, I.Z.; Dimaggio, P. A.; Beltran, A.; Mishra, N.; LeRoy, G.; Floudas, C. A.; Garcia, B.A., Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a. Journal of the American Society for Mass Spectrometry, 2010, 21, (5), 960-970.

A de novo method for untargeted identification of post-translational modifications via tandem mass spectrometry

Baliban, R. C.; Dimaggio, P. A.; Plazas-Mayorca, M.D.; Young, N. L.; Garcia, B. A.; Floudas, C. A., A de novo method for untargeted identification of post-translational modifications via tandem mass spectrometry. Mol Cell Proteomics, 2010, 9, (5), 764-79.

Systems-wide proteomic caracterization of combinatorial post-translational modification patterns

Young, N.L.; Plazas-Mayorca, M.D.; Garcia, B.A. Systems-wide proteomic caracterization of combinatorial post-translational modification patterns. Expert Rev. in Proteomics, 2010, 7, (1), 79-92.

Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination for post-translational modifications

Garske, A.L.; Oliver, S.S.; Wagner, E.K.; Musselman, C.; LeRoy, G.; Garcia, B.A.; Kutateladze, T.; Denu, J.M., Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination for post-translational modifications. Nature Chem. Biol. 2010, (4), 283-90.

In vivo residue-specific histone methylation dynamics

Zee B.M.; Levin, R.S.; Xu, B.; LeRoy, G.; Wingreen, N.S.; Garcia, B.A., In vivo residue-specific histone methylation dynamics. Journal of Biological Chemistry, 2010, 285, (5), 3341-50.

What does the future hold for top down mass spectrometry?

Garcia, B.A., What does the future hold for top down mass spectrometry? Journal of the American Society for Mass Spectrometry, 2010, 21, (2), 193-202.

Electron transfer dissociation facilitates sequencing of ADP-ribosylated peptides

Zee, B.M.; Garcia, B.A., Electron transfer dissociation facilitates sequencing of ADP-ribosylated peptides. Analytical Chemistry, 2010. 82, (1), 28-31.